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Results Cryo-EM structure of human DDB1-DDA1-DET1 (DDD) complex To gain structural insights into the assembly of the DDD complex, we co-transfected DDB1, DDA1 and DET1 into Expi293F cells and purified the complex using a tandem affinity purification protocol (Fig

Impact of age-related genetic differences on the therapeutic outcome of papillary thyroid cancer

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How Berberine and Metformin Work Understanding the mechanisms of action of both berberine and metformin helps explain why their combination requires medical oversight